Millipore Sigma Vibrant Logo

551600 Quercetin, Dihydrate - CAS 6151-25-3 - Calbiochem

Overview

Key Specifications Table

CAS #Empirical Formula
6151-25-3C₁₅H₁₀O₇ · 2H₂O

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
551600-100MG
Limited Availability
Limited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Glass bottle 100 mg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewA cell-permeable and reversible inhibitor of PIM1 kinase (IC50 = 43 nM), PI 3-K (IC50 = 3.8 µM) and phospholipase A2 (IC50 = 2 µM). Also inhibits mitochondrial ATPase, phosphodiesterases, and protein kinase C. Induces apoptosis in K562, Molt-4, Raji, and MCAS tumor cell lines. Reported to activate sirtuins and promote the survival of eukaryotic cells.
      Catalogue Number551600
      Brand Family Calbiochem®
      Synonyms3,3ʹ,4ʹ,5,7-Pentahydroxyflavone
      References
      ReferencesBullock, A.N., et al. 2005. J. Med. Chem. 48, 7604.
      Howitz, K.T., et al. 2003. Nature 425, 191.
      Wei, Y.Q., et al. 1994. Cancer Res. 54, 4952.
      Shibasaki, F., et al. 1993. Biochem. J. 289, 227.
      Matter, W.F., et al. 1992. Biochem. Biophys. Res. Comm. 186, 624.
      Levy, J., et al. 1984. Biochem. Biophys. Res. Commun. 123, 1227.
      Graziani, Y., et al. 1983. Eur. J. Biochem. 135, 583.
      Gschwendt, M., et al. 1983. Biochem. Biophys. Res. Commun. 117, 444.
      Ruckstuhl, M., et al. 1979. Biochem. Pharmacol. 28, 535.
      Beretz, A., et al. 1978. Experientia 34, 1054.
      Product Information
      CAS number6151-25-3
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₁₅H₁₀O₇ · 2H₂O
      Chemical formulaC₁₅H₁₀O₇ · 2H₂O
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetPI 3-kinase
      Primary Target IC<sub>50</sub>43 nM, 3.8 µM, 2 µM against PIM1 kinase, PI 3-K, and phospholipase A2, respectively
      Purity>95% by HPLC
      Physicochemical Information
      Cell permeableY
      Safety Information according to GHS
      RTECSLK8950000
      Safety Information
      R PhraseR: 25-40

      Toxic if swallowed.
      Limited evidence of a carcinogenic effect.
      S PhraseS: 36/37/39-45

      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 months at 4°C.
      Global Trade Item Number
      Catalog Number GTIN
      551600-100MG 07790788051426