Performance
ProteinAGProteinAG
Human lgG1 ++ ++ Rat lgM +/-- --
Human lgG2 ++ ++ Rabbit lgG ++ ++
Human lgG3 -- ++ Hamster lgG + ++
Human lgG4 ++ ++ Guinea Pig lgG ++ +
Human lgA + -- Bovine lgG + +
Human lgD + -- Sheep lgG +/-- +
Human lgE + -- Goat lgG +/-- +
Human lgM + -- Pig lgG ++ ++
Mouse lgG1 + + Chicken lgG -- +/--
Mouse lgG2a ++ ++ Fragments
Mouse lgG2b ++ ++ Human Fab + +
Mouse lgG3 + ++ Human F(ab)2 + +/--
Mouse lgM +/-- -- Human ScFv + --
Rat lgG ++ ++ Human Fc + --
Rat lgG1 +/-- + Human K -- --
Rat lgG2a +/-- ++ Human -- +
Rat lgG2b +/-- +

Binding Affinities of Protein A and G
Legend: ++ = Strong affinity; + = Moderate/slight affinity; 
+/-- = Requires evaluation; -- = No affinity