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Faster Sample Processing Compared to Manual Syringe Filtration
Using the steps indicated (below the table*), sample processing time was compared between the Samplicity® G2 filtration system and manual syringe filtration, processing eight samples at a time, using a variety of Millex® device types** and test solutions. The Samplicity® G2 filtration system afforded time savings in all cases tested.Click here to download the application note!
| Sample Type | Samplicity® G2 Filtration System time benefit over manual syringe (per 8 samples) | Samplicity® G2 Filtration System processing time (minutes; 8 samples) | (10 mL) Syringe processing time (minutes; 8 samples) | |||
|---|---|---|---|---|---|---|
| Min. | Max. | Min. | Max. | Min. | Max. | |
| Milli-Q® Water | 54% | 62% | 1.88 | 2.08 | 4.08 | 5.22 |
| Dissolution Testing | 40% | 49% | 2.23 | 2.68 | 3.85 | 5.17 |
| 5% Ketchup | 28% | 60% | 3.10 | 4.15 | 4.93 | 9.23 |
*Steps performed for each method:
Each step was timed in order to assess processing speed for 8 samples.
| A. Samplicity® G2 Filtration System | B. Manual Syringe Filtration | |
|---|---|---|
| 1. Insert 8 HPLC vials into base | 1. Unwrap syringe | Repeat these steps 8 times total. |
| 2. Insert 8 Millex® filters** into lid | 2. Pull sample into syringe | |
| 3. Insert 8 funnels into Millex® filters | 3. Attach Millex® filter to syringe | |
| 4. Pipette 8 samples into funnels | 4. Push plunger to filter the sample | |
| 5. Turn vacuum on | ||
| 6. Discard funnels and filters | ||
| 7. Disassemble and remove vials |
**Refers to Millex® Filters for the Samplicity® G2 System. Specific filters tested were 0.22 μm Durapore® PVDF, 0.45 μm Durapore® PVDF, 0.22 μm Millipore Express® PLUS PES, 0.45 μm Millipore Express® PLUS PES, 0.20 μm nylon, and 0.45 μm nylon.
For Optimum Speed Advantage, Choose Millex Samplicity® Filters
Overall time savings using Samplicity® filtration system compared to syringe filtration.To compare the speed of the Samplicity® system compared to syringe filtration, either four or eight 1.0 mL samples of 1% Pepto-Bismol were filtered by 15 timed users, either through hydrophilic polytetrafluoroethylene (PTFE) Millex syringe filters with a 10 mL syringe, or through 0.45 µm hydrophilic PTFE Millex Samplicity® membrane filters using the Samplicity® filtration system. Pre-launch Device Disclaimer: The information presented is based on preliminary development results. Device performance in specific applications may be different.
The Samplicity® Filtration system enables higher yields for small sample volumes: low holdup volume enables you to do more analyses with each precious sample.