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Buffer Detection Kit for Magnetic Beads
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505419
Sigma-Aldrichα,β-methylene ATP - CAS 104809-20-3 - Calbiochem
A metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.
Sawyer, G.W., et al. 2000. Br. J. Pharmacol.129, 1458. Komori, S., et al. 1988. Br. J. Pharmacol.94, 9.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.
Form
White powder
CAS number
104809-20-3
Chemical formula
C₁₁H₁₈N₅O₁₂P₃ • xLi+
Structure formula
Purity
≥93% by HPLC
Solubility
H₂O (100 mg/ml)
Storage
Protect from light
-20°C
Hygroscopic
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Sawyer, G.W., et al. 2000. Br. J. Pharmacol.129, 1458. Komori, S., et al. 1988. Br. J. Pharmacol.94, 9.
