548000 Sigma-Aldrich1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem
Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.
More>> Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Less<<Synonyms: APDC, Ammonium Pyrrolidinedithiocarbamate, PDTC, NH₄
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Overview
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Key Specifications Table
CAS # | Empirical Formula |
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5108-96-3 | C₅H₁₂N₂S₂ |
Products
Catalog Number | Packaging | Qty/Pack | |
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548000-100MG | Plastic ampoule | 100 mg |
Product Information | |
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CAS number | 5108-96-3 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₅H₁₂N₂S₂ |
Chemical formula | C₅H₁₂N₂S₂ |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | Induction of nitric oxide synthase activity in rat alveolar macrophages |
Purity | ≥98% by titration |
Physicochemical Information | |
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Cell permeable | Y |
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Materials Information |
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Safety Information according to GHS |
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Product Usage Statements |
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Packaging Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalog Number | GTIN |
548000-100MG | 07790788051419 |
Documentation
1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem SDS
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1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem Certificates of Analysis
Title | Lot Number |
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548000 |
References
Reference overview |
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Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667. Pan, Z., et al. 1995. J. Biol. Chem. 270, 7787. Bessho, R., et al. 1994. Biochem. Pharmacol. 48, 1883. Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun. 191, 1301. Schreck, R., et al. 1992. J. Exp. Med. 175, 1181. |
Brochure
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Pathways and Biomarkers of Oxidative Stress |
Citations
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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