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107478 1,2-Propanediol

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
57-55-6200-338-0C₃H₈O₂CH₃CH(OH)CH₂OH76.09 g/molPh Eur,BP,USP

Products

Catalog NumberPackaging Qty/Pack
1074782500 Plastic bottle 2.5 l
1074786025 Drum stainl. st. 25 l
1074786190 Drum stainl. st. 190 l
Description
Catalogue Number107478
Synonyms1,2-Propylene glycol
Description1,2-Propanediol
References
Product Information
CAS number57-55-6
EC number200-338-0
GradePh Eur,BP,USP
Hill FormulaC₃H₈O₂
Chemical formulaCH₃CH(OH)CH₂OH
Molar Mass76.09 g/mol
HS Code2905 32 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point188 °C (1013 hPa)
Density1.036 g/cm3 (25 °C)
Explosion limit2.4 - 17.4 %(V)
Flash point99 °C
Ignition temperature371 °C
Melting Point-59 °C
pH value6 - 8 (100 g/l, H₂O, 20 °C)
Vapor pressure0.2 hPa (25 °C)
Refractive Index1.43 (20 °C)
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 19400 - 36000 mg/kg
LD 50 dermalLD50 Rabbit 20800 mg/kg
Safety Information according to GHS
RTECSTY2000000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Purity (GC)≥ 99.5 %
Identity (IR)conforms
Identity D (Ph Eur)**121 - 128 °C
Appearance of the substanceconforms
Density (d 20 °C/20 °C)1.035 - 1.040
Density (d 25 °C/25 °C)1.035 - 1.037
Refractive index (n 20/D)1.431 - 1.433
Boiling point184 - 189 °C
Acidityconforms
Chloride (Cl)≤ 0.007 %
Sulfate (SO₄)≤ 0.006 %
Isomers of dipropylene glycolconforms
Diethylene glycol (GC)≤ 0.10 %
Ethylenglycol (GC)≤ 0.10 %
Residual solvents (ICH Q3C)excluded by production process
Oxidizing Substancesconforms
Reducing substancesconforms
Sulfated ash≤ 0.007 %
Water≤ 0.20 %
Bacterial endotoxins≤ 2.5 I.U./ml
Total aerobic microbial count (TAMC)≤ 10²
Total combined yeasts/moulds count (TYMC)≤ 10¹
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
**The value of the additional identity test is transferred from the supplier CoA.
Conforms to Ph Eur, BP, USP
Global Trade Item Number
Catalog Number GTIN
1074782500 04022536091136
1074786025 04022536091167
1074786190 04022536091174

Documentation

Material Qualification Dossier

TitleVersion
8.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

1,2-Propanediol SDS

Title

Safety Data Sheet (SDS) 

1,2-Propanediol Certificates of Analysis

Product Number PackagingSpecificationLot Number
1074782500 Plastic bottlePDF Specification Document
1074786025 Drum stainl. st.PDF Specification Document
1074786190 Drum stainl. st.PDF Specification Document

Certificates

Title