100050 Sigma-Aldrich1400W - CAS 214358-33-5 - Calbiochem
A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM).
More>> A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM). Less<<Synonyms: N-(3-Aminomethyl)benzylacetamidine, 2HCl
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Overview
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Key Specifications Table
CAS # | Empirical Formula |
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214358-33-5 | C₁₀H₁₅N₃ · 2HCl |
Products
Catalog Number | Packaging | Qty/Pack | |
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100050-5MG | Plastic ampoule | 5 mg |
Product Information | |
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CAS number | 214358-33-5 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₁₀H₁₅N₃ · 2HCl |
Chemical formula | C₁₀H₁₅N₃ · 2HCl |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | iNOS |
Primary Target IC<sub>50</sub> | Kd = 7 nM against inducible nitric oxide synthase (iNOS) |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Transport Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalog Number | GTIN |
100050-5MG | 04055977226867 |
Documentation
1400W - CAS 214358-33-5 - Calbiochem SDS
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1400W - CAS 214358-33-5 - Calbiochem Certificates of Analysis
Title | Lot Number |
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100050 |
References
Reference overview |
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Parmentier, S., et al. 1999. Br. J. Pharmacol. 127, 546. Cardenas, A., et al. 1998. Eur. J. Pharmacol. 354, 161. Parrino, P.E., et al. 1998. Ann. Thorac. Surg. 66, 733. Garvey, E.P., et al. 1997. J. Biol. Chem. 272, 4959. Laszlo, F., and Whittle, B.J. 1997. Eur. J. Pharmacol. 334, 99. Thomsen, L.L., et al. 1997. Cancer Res. 57, 3300. |
Brochure
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Pathways and Biomarkers of Oxidative Stress |
Citations
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Data Sheet | ||||||||||||||||||||||||||||||||
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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