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504472 (2R,4R)-APDC - CAS 169209-63-6 - Calbiochem

(2R,4R)-APDC - CAS 169209-63-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate, APDC

Primary Target: mGlu₂ and mGlu₃
504472
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
169209-63-6C₆H₁₀N₂O₄

Products

Catalog NumberPackaging Qty/Pack
5.04472.0001 Glass bottle 1 mg
Description
OverviewA highly selective and potent agonist for group II metabotropic glutamate receptor (EC50 = 0.4, 0.4, > 100, > 100, > 300 and > 300 µM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4 and mGlu7 receptors respectively). Used as anti- and pro-convulsant, neuroprotectant, antinociceptive, and addiction treatment.
Catalogue Number504472
Brand Family Calbiochem®
Synonyms(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate, APDC
References
ReferencesFolbergrová, J., et al. 2005. Experimental Neurology. 192, 420.
Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav. 73, 411.
Schoepp, D., et al. 1995. Neuropharmacology. 34, 843.
Monn, J., et al. 1996. J. Med. Chem. 39, 2990.
Product Information
CAS number169209-63-6
FormOff-white powder
Hill FormulaC₆H₁₀N₂O₄
Chemical formulaC₆H₁₀N₂O₄
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetmGlu₂ and mGlu₃
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.04472.0001 04055977264142

Documentation

(2R,4R)-APDC - CAS 169209-63-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Folbergrová, J., et al. 2005. Experimental Neurology. 192, 420.
Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav. 73, 411.
Schoepp, D., et al. 1995. Neuropharmacology. 34, 843.
Monn, J., et al. 1996. J. Med. Chem. 39, 2990.

Brochure

Title
Pathways and Biomarkers of Glutamatergic Synapse Flyer
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-August-2017 JSW
Synonyms(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate, APDC
DescriptionA highly selective and potent agonist for group II metabotropic glutamate receptor (EC50 = 0.4, 0.4, > 100, > 100, > 300 and > 300 µM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4 and mGlu7 receptors respectively). Used as anti- and pro-convulsant, neuroprotectant, antinociceptive, and addiction treatment.
FormOff-white powder
CAS number169209-63-6
Chemical formulaC₆H₁₀N₂O₄
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesFolbergrová, J., et al. 2005. Experimental Neurology. 192, 420.
Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav. 73, 411.
Schoepp, D., et al. 1995. Neuropharmacology. 34, 843.
Monn, J., et al. 1996. J. Med. Chem. 39, 2990.