| 07-667 | Anti-APP Antibody
| synthetic peptide corresponding to amino acids 44-61 of human Amyloid Precursor Protein (APP)
| Rabbit
| Immunoprecipitation,
Western Blotting
| APP
| Human,
Rat,
Mouse
|
| AB1593 | Anti-Amyloid Precursor Protein Antibody, a.a. 44-63
| Peptide to the N-terminal region (amino acids 44-63) of the APP protein.
| Goat
| ELISA,
Immunofluorescence,
Western Blotting,
Immunohistochemistry,
Immunohistochemistry (Paraffin)
| Recognizes amyloid precursor protein (APP). In Alzheimer's disease, this protein is broken down and releases the 12 amino acid b-amyloid protein that is found in senile plaques and vessels. <br /><br />The amyloid precursor protein is the subject of intensive investigations to determine how this protein is broken down abnormally in Alzheimer's disease to give rise to the b-amyloid protein which is present in senile plaques and vessels. This antiserum has been shown to be immunoreactive to the immunizing peptide by ELISA. The antiserum will immunolabel dystrophic neurites in senile plaques in both formalin-fixed paraffin sections and paraformaldehyde fixed frozen sections from Alzheimer's brain. <br /><br />This antiserum should be a valuable tool for scientist and neuropathologists who study the role of amyloid in Alzheimers's disease.
| Human
|
| AB5300 | Anti-Amyloid Precursor Protein Antibody, universal
| APP (aa 99-126) conjugated to KLH.
| Rabbit
| Immunoprecipitation,
Western Blotting
| Amyloid Precursor Protein (APP), Universal. Specific to amino acids 99-126.
| Human,
Mouse,
Monkey
|
| AB5302 | Anti-Amyloid Precursor Protein Antibody, KPI Domain
| APP.
| Rabbit
| Immunoprecipitation,
Western Blotting,
Immunocytochemistry,
Immunohistochemistry
| Amyloid Precursor Protein (APP), KPI Domain.
| Bovine,
Human,
Mouse,
Monkey
|
| AB5988P | Anti-Amyloid Precursor Protein Antibody, Domain 770
| Synthetic peptide corresponding to the OX2 domain of APP770.
| Rabbit
| Immunoprecipitation,
Western Blotting,
Immunocytochemistry,
Immunohistochemistry
| Amyloid precursor protein (APP), domain 770, but not APP751 or APP695.
| Human,
Monkey
|
| FCMAB327F | Anti-Alzheimer Precursor Protein A4 (NT)-FITC Antibody, clone 22C11
| Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein.
| Mouse
| Flow Cytometry
| Antibody recognizes Alzheimer Precursor Protein
| Canine
|
| IHCR1002-6 | Anti-APP A4 Antibody, a.a. 66-81 (NT), Prediluted, clone 22C11
| Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein.
| Mouse
| Immunohistochemistry (Paraffin)
| The antibody recognizes amino acids 66-81 of the N-terminus on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP, immature ~110kDa, sAPP ~120kDa, and mature ~130kDa (Hoffmann et al., 2000). The antibody is known to cross react with APLP2 (Slunt, 1994).
| Canine,
Human,
Mouse,
Monkey,
Pig,
Rat,
Fish
|
| MAB343 | Anti-APP Antibody, APP 643-695 CT fragment, clone 2.F2.19B4
| Carboxyl fragment of APP 643-695 / Jonas.
| Mouse
| Immunohistochemistry (Paraffin),
Western Blotting
| Reacts with intact full-length Alzheimer precursor protein (APP) and selectively with the cytoplasmic carboxyl fragment of APP 643-695. Epitope has reportedly been mapped in this paper http://www.impub.co.uk/abs/W386.html
| Human,
Rat
|
| MAB348 | Anti-APP A4 Antibody, a.a. 66-81 of APP {NT}, clone 22C11
| Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein.
| Mouse
| Immunocytochemistry,
Immunofluorescence,
Immunohistochemistry,
Immunohistochemistry (Paraffin),
Western Blotting
| Reacts with pre-A4. The antibody recognizes amino acids 66-81 of the N-terminus on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP, immature ~110kDa, sAPP ~120kDa, and mature ~130kDa (Hoffmann et al., 2000). The antibody is known to cross react with APLP2 (Slunt, 1994).
| Canine,
Human,
Mouse,
Monkey,
Pig,
Rat,
Fish
|
| MAB348-100UL | Anti-APP A4 Antibody, a.a. 66-81 of APP (NT), clone 22C11
| Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein.
| Mouse
| Immunofluorescence,
Immunohistochemistry,
Immunohistochemistry (Paraffin),
Western Blotting
| Reacts with pre-A4. The antibody recognizes a N-terminal epitope on the pre-A4 molecule
| Human,
Mouse,
Rat,
Monkey,
Pig,
Fish
|
| MAB348A4 | Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Alexa Fluor® 488 conjugate
| Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein
| Mouse
| Immunohistochemistry,
Immunocytochemistry
| Unconjugated MAB348 recognizes N-terminal amino acids 66-81 on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP: immature, ~110kDa; sAPP, ~120kDa; and mature, ~130kDa (Hoffmann et al., 2000). This antibody is known to cross react with APLP2 (Slunt, 1994).
| Rat,
Mouse,
Human,
Monkey,
Pig,
Canine
|
| MAB348B | Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Biotin Conj.
| Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein
| Mouse
| Immunohistochemistry,
Immunocytochemistry
| This antibody recognizes Alzheimer Precursor Protein A4 at the N-temrinus.
| Rat,
Mouse,
Canine,
Human,
Monkey,
Pig
|
| MAB349 | Anti-Amyloid Precursor Protein Antibody, A4(695), clone 1.D5
| Synthetic peptide Alz 90 [amino acids 511-608 of amyloid precursor protein pre A4(695)].
| Mouse
| Western Blotting
| Reacts with the natural amyloid precursor protein A4(695).
| Human,
Rat
|
| MAB5228 | Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84
| Amyloid Precursor Protein (APP) secreted by the EJ-1 bladder carcinoma cell line.
| Mouse
| ELISA,
Western Blotting
| Reacts with secretory amyloid precursor protein (sAPP), but not with Amyloid-Beta protein 1-40.
| Human
|
| MAB5354 | Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1
| Purified recombinant KPI domain of Amyloid-beta precursor protein.
| Mouse
| ELISA,
Western Blotting,
Immunohistochemistry
| Amyloid-beta Precursor Protein, KPI (Kunitz protease inhibitor) domain. The antibody reacts with both native and recombinant protein. The antibody has been shown to partially inhibit protease inhibitory properties.
| Human
|
| MABN380 | Anti-APP-C99 Antibody, clone mC99(70–80)
| Recombinant protein corresponding to Human APP-C99.
| Mouse
| Western Blotting,
Immunoprecipitation,
Immunohistochemistry,
Immunofluorescence
| | Human,
Mouse
|
| MABN381 | Anti-APP-C99 Antibody, clone mC99(1-7)
| Recombinant protein corresponding to Human APP-C99.
| Mouse
| Western Blotting,
Immunoprecipitation,
Immunocytochemistry,
Immunohistochemistry
| | Human,
Mouse
|
