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09-278 Anti-20S proteasome subunit β5 Antibody

This Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.

Anti-20S proteasome subunit β5 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Protein Trafficking Research Sub-Category: Ubiquitin & Ubiquitin Metabolism Gene Symbol: PSMB5, X, LMPX, MGC104214, MB1 UniProt Number: P28074
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09-278
100 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIHC, WBRbSerumPolyclonal Antibody
Description
Catalogue Number09-278
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-20S proteasome subunit β5 Antibody
Alternate Names
  • LMP17
  • MB1
References
Product Information
FormatSerum
HS Code3002 15 90
Presentation100 µL of purified antiserum preparation in PBS containing 0.09% sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
Quality LevelMQ100
Applications
ApplicationThis Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Biological Information
ImmunogenPeptide corresponding to residues 194-207 of human proteasome subunit β5 conjugated to KLH.
HostRabbit
SpecificityRecognizes proteasome subunit β5
IsotypeIgG
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).
Gene Symbol
  • PSMB5
  • X
  • LMPX
  • MGC104214
  • MB1
Purification Methodantiserum
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P28074 # The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May catalyze basal processing of intracellular antigens.
SIZE: 208 amino acids; 22897 Da
SUBUNIT: The proteasome is composed of at least 15 non identical subunits which form a highly ordered ring-shaped structure. This subunit can be displaced by the equivalent immune-specific subunit PSMB8. Directly interacts with POMP.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
SIMILARITY: SwissProt: P28074 ## Belongs to the peptidase T1B family.
Molecular Weight22 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of shipment for up to 12 months.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
09-278 04053252329722

Documentation

Anti-20S proteasome subunit β5 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-20S proteasome subunit β5 Antibody Certificates of Analysis

TitleLot Number
Anti-20S proteasome subunit B5 (Rabbit polyclonal IgG) 2896040
Anti-20S proteasome subunit b5 (Rabbit polyclonal IgG) - 2356118 2356118
Anti-20S proteasome subunit b5 - NG1723300 NG1723300
Anti-20S proteasome subunit b5 - NG1812470 NG1812470
Anti-20S proteasome subunit b5 - NG1879750 NG1879750
Anti-20S proteasome subunit b5 - NG1883531 NG1883531
Anti-20S proteasome subunit b5 -2700321 2700321
Anti-20S proteasome subunit beta;5 - 0611046110 0611046110
Anti-20S proteasome subunit β5 (Rabbit polyclonal IgG) - 2452694 2452694
Anti-20S proteasome subunit β5 (Rabbit polyclonal IgG) 3120570
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References

Reference overviewPub Med ID
The 26S proteasome: subunits and functions
Tanaka, K and Tsurumi, C
Mol Biol Rep, 24:3-11 (1997)  1997

9228274 9228274