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AB10340 Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A

Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Toxicology & Drug Resistance Gene Symbol: ABC-1 , ABC1 , CERP, FLJ14958, HDLDT1 , MGC164864, MGC165011, OTTHUMP00000021833, TGD, membrane-bound
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AB10340
50 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWBRbSerumPolyclonal Antibody
Description
Catalogue NumberAB10340
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A
Alternate Names
  • ATP binding cassette transporter 1
  • ATP-binding cassette 1
  • ATP-binding cassette transporter 1
  • ATP-binding cassette, sub-family A (ABC1), member 1
  • ATP-binding cassette, sub-family A member 1
  • ATP-binding cassette, sub-family A, member 1
  • Cholesterol efflux regulatory protein
Background InformationThis protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.
References
Product Information
FormatSerum
PresentationRaw rabbit serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.
Biological Information
ImmunogenRecombinant
EpitopeAA N629 – W704
HostRabbit
Species Reactivity
  • Mouse
  • Rat
Species Reactivity NoteMouse. Expected to react with rat based on sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq]
Gene Symbol
  • ABC-1
  • ABC1
  • CERP
  • FLJ14958
  • HDLDT1
  • MGC164864
  • MGC165011
  • OTTHUMP00000021833
  • TGD
  • membrane-bound
Molecular Weight141 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C for up to 12 months from date of receipt.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
AB10340 04053252625886

Documentation

Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A SDS

Title

Safety Data Sheet (SDS) 

Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A Certificates of Analysis

TitleLot Number
Anti-ATP-binding cassette, sub-family -2786960 2786960
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A - 2830164 2830164
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A - NG1556732 NG1556732
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A -2893623 2893623
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A Polyclonal Antibody 3023593

References

Reference overviewPub Med ID
mRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cells.
Sike, A; Nagy, E; Vedelek, B; Pusztai, D; Szerémy, P; Venetianer, A; Boros, IM
PloS one  9  e84915  2014

Show Abstract 		24409311 24409311