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MABE627 Anti-AURKB, clone 13E8D3 Antibody

MABE627
100 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMAscitesMonoclonal Antibody
Description
Catalogue NumberMABE627
Replaces04-1036
DescriptionAnti-AURKB, clone 13E8D3 Antibody
Alternate Names
  • Aurora kinase B
  • AURKB
Background InformationAurora A, B, and C, are members of the serine/threonine kinase family. These have been identified as important regulators of the mitotic cell division process. Aurora B, specifically, is involved in the regulation of centrosome function, bipolar spindle assembly, and chromosome segregation. Aurora-C is a chromosomal passenger protein that form complexes with Aurora B and INCENP (which binds and activates Aurora C in vivo and in vitro).
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-AURKB, clone 13E8D3 Antibody is an antibody against AURKB for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenPurified recombinant fragment of AURKB expressed in E. Coli.
Clone13E8D3
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • AURKB
  • AIK2
  • AIM1
  • AIRK2
  • ARK2
  • STK1
  • STK12
  • STK5
Purification MethodUnpurified
UniProt Number
Molecular Weight~22 and ~43 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in truncated AURKB recombinant protein and SKN-SH cell lysate.

Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected truncated AURKB recombinant protein and SKN-SH cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABE627 04055977172256