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MAB3502-I Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Signaling Neuroscience Gene Symbol: ACE, DCP, DCP1 UniProt Number: P12821
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MAB3502-I
100 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBMCulture SupernatantMonoclonal Antibody
Description
Catalogue NumberMAB3502-I
ReplacesMAB3502
DescriptionAnti-Angiotensin Converting Enzyme Antibody, clone 2E2
Alternate Names
  • Angiotensin-converting enzyme
  • ACE
  • Dipeptidyl carboxypeptidase I
  • Kininase II
  • CD143
Background InformationAngiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.
References
Product Information
FormatCulture Supernatant
HS Code3002 15 90
Control
  • Rat Angiotensin Converting Enzyme
PresentationMouse monoclonal IgG1 cultured supernatant without preservatives.
Quality LevelMQ100
Applications
ApplicationAnti-Angiotensin Converting Enzyme Antibody, clone 2E2.
Key Applications
  • Western Blotting
Biological Information
ImmunogenHuman Angiotensin Converting Enzyme.
Clone2E2
HostMouse
IsotypeIgG1
Species Reactivity
  • Rat
Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human based on immunogen design.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ACE
  • DCP
  • DCP1
Purification MethodUnpurified
UniProt Number
Molecular Weight~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in rat Angiotensin Converting Enzyme.

Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MAB3502-I 04053252441509