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ABT180 Anti-CDCP1 Antibody

Anti-CDCP1 Antibody is a highly specific rabbit polyclonal antibody, that targets CUB domain-containing protein 1 & has been tested in western blotting & IHC (Paraffin).

Anti-CDCP1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: ECM Proteins Gene Symbol: CDCP1, TRASK UniProt Number: Q9H5V8
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ABT180
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT180
DescriptionAnti-CDCP1 Antibody
Alternate Names
  • CUB domain-containing protein 1
  • Membrane glycoprotein gp140
  • Subtractive immunization M plus HEp3-associated 135 kDa protein
  • SIMA135
  • Transmembrane and associated with src kinases
  • CD318
Background InformationCUB domain-containing protein 1 (CDCP1) is also called Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein (SIMA135), Transmembrane and associated with src kinases and CD_antigen 318. CDCP1 is part of the tetraspanin web involved in tumor progression and metastasis. CDCP1 may also be involved in cell adhesion, cell matrix association and regulation of anchorage versus migration or proliferation versus differentiation via phosphorylation status. CDCP1 is a possible marker for leukemia diagnosis, and for subsets of immature hematopoietic stem cell. CDCP1 is highly expressed in mitotic cells, skeletal muscle, colon, many human tumor cell lines, colorectal cancer, breast carcinoma and lung cancer. CDCP1 may also be found in cells phenotypically similar to mesenchymal stem cells and neural stem cells.
References
Product Information
FormatAffinity Purified
Control
  • Human pancreas tumor tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-CDCP1 Antibody is a highly specific rabbit polyclonal antibody, that targets CUB domain-containing protein 1 & has been tested in western blotting & IHC (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesWestern Blotting Analysis: 2 µg/mL of this antibody detected CDCP1 in a panel of human tumor tissue lysates.

Immunohistochemistry Analysis: A 1:100 and a 1:500 dilution from a representative lot detected CDCP1 in human breast carcinoma sections.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human CDCP1.
EpitopeCytoplasmic domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the cytoplasmic domain of CDCP1.
Species Reactivity
  • Human
Species Reactivity NoteDemonstrated to react with Human. Other Homologies: Mouse and Rat (77% sequence homology).
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • CDCP1
  • TRASK
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~135 kDa and ~70 kDa observed. Uniprot describes 3 isoforms at 92 kDa, 72 kDa, and 38 kDa, due to alternative splicing. The full length and cleaved form of CDCP1 have been observed at ~135 kDa and ~70 kDa (Casar, B., et al. (2012). Oncogene 31(35):3924-3938.). Uncharacterized band(s) may be observed in some cell lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human pancreas tumor tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CDCP1 in 10 µg of human pancreas tumor tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABT180 04053252914713

Documentation

Anti-CDCP1 Antibody Certificates of Analysis

TitleLot Number
Anti-CDCP1 - Q2208851 Q2208851