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AB10320 Anti-Cytochrome P450 1B1 Antibody

Anti-1B1 Antibody detects level of 1B1 & has been published & validated for use in WB.

Anti-Cytochrome P450 1B1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Enzymes & Biochemistry Gene Symbol: CP1B, CYPIB1 , EC 1.14.14.1 , GLC3A UniProt Number: Q16678
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AB10320
50 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbSerumPolyclonal Antibody
Description
Catalogue NumberAB10320
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Cytochrome P450 1B1 Antibody
Alternate Names
  • Cytochrome P450 1B1
Background InformationCytochrome P450 1B1 (CYP1B1) is active in the metabolism of estrogens to reactive catechols and of different procarcinogens. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids.
References
Product Information
FormatSerum
PresentationRaw rabbit serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-1B1 Antibody detects level of 1B1 & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application NotesSuggested dilutions:
Western Blot: 1:5000
Biological Information
ImmunogenRecombinant human 1B1
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Gene Symbol
  • CP1B
  • CYPIB1
  • EC 1.14.14.1
  • GLC3A
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q16678 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
SIZE: 543 amino acids; 60846 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
SIMILARITY: SwissProt:Q16678 # Belongs to the cytochrome P450 family.
Molecular Weight61kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by immunoblot.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C for up to 12 months from date of receipt.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
AB10320 04053252583070