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ABS236 Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526

This Cytochrome P450 (scc) antibody is validated for use in WB & IHC for the detection of the Cytochrome P450 (scc) protein.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: Cyp11a1, Cyp11a, Cyp11a-1 UniProt Number: P14137
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ABS236
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS236
ReplacesAB1294
DescriptionAnti-Cytochrome P450 (scc) Antibody, a.a. 509-526
Alternate Names
  • Cholesterol side-chain cleavage enzyme, mitochondrial
  • CYPXIA1
  • Cholesterol desmolase
  • Cytochrome P450 11A1
  • Cytochrome P450(scc)
Background InformationAs a member of the cytochrome P450 family, Cytochrome P450 Side Chain Cleavage Enzyme (scc) catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone during the first step of steroid biosynthesis. It is expressed in certain organs, such as ovaries, adrenal glands, and testis. Deficiency in CYP11A1 is commonly associated with adrenal insufficiency, and with variable degrees of disorder of sex development (DSD).
References
Product Information
FormatAffinity Purified
Control
  • Rat adrenal tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Cytochrome P450 (scc) antibody is validated for use in WB & IHC for the detection of the Cytochrome P450 (scc) protein.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Cytochrome P450 (scc) in rat adrenal gland and rat testis tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of rat Cytochrome P450 (scc), a.a. 509-526.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of Cytochrome P450 (scc), a.a. 509-526.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Cyp11a1
  • Cyp11a
  • Cyp11a-1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~52 kDa observed. On higher percentage gels and longer exposures, 8 kDa cleavage product can be detected.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in rat adrenal tissue lysate.

Western Blot Analysis: 0.02 µg/mL of this antibody detected Cytochrome P450 (scc) in 10 µg of rat adrenal tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABS236 04053252847738

Documentation

Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526 SDS

Title

Safety Data Sheet (SDS) 

Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526 Certificates of Analysis

TitleLot Number
Anti-Cytochrome P450 (scc), a.a. 509-526 - Q2115841 Q2115841
Anti-Cytochrome P450 (scc), a.a. 509-526 - 2986142 2986142
Anti-Cytochrome P450 (scc), a.a. 509-526 - 3267891 3267891
Anti-Cytochrome P450 (scc), a.a. 509-526 - 3546847 3546847
Anti-Cytochrome P450 (scc), a.a. 509-526 - 3944548 3944548
Anti-Cytochrome P450 (scc), a.a. 509-526 -2503030 2503030
Anti-Cytochrome P450 (scc), a.a. 509-526 -2683268 2683268