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MABD120 Anti-FGFR4 Antibody, clone 4H2B10B2

Detect FGFR4 using this mouse monoclonal antibody, Anti-FGFR4 Antibody, clone 4H2B10B2 validated for use in western blotting & IHC.

Anti-FGFR4 Antibody, clone 4H2B10B2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: FGFR4 UniProt Number: G3JVM2
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MABD120
100 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMAscitesMonoclonal Antibody
Description
Catalogue NumberMABD120
DescriptionAnti-FGFR4 Antibody, clone 4H2B10B2
Alternate Names
  • Fibroblast growth factor receptor
Background InformationFGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that plays an important role in the biological functions of specific growth factors. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
References
Product Information
FormatAscites
Control
  • HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA
PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect FGFR4 using this mouse monoclonal antibody, Anti-FGFR4 Antibody, clone 4H2B10B2 validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected FGFR4 in human liver tissue.

Optimal working dilutions must be determined by end user.

Biological Information
ImmunogenPurified recombinant fragment of human FGFR4 expressed in E. Coli.
Clone4H2B10B2
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • FGFR4
Purification MethodUnpurified
UniProt Number
Molecular Weight~88 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA .

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected FGFR4 in HEK293T cells transfected with pCMV6-ENTRY FGFR4 cDNA.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABD120 04053252916434

Documentation

Anti-FGFR4 Antibody, clone 4H2B10B2 SDS

Title

Safety Data Sheet (SDS) 

Anti-FGFR4 Antibody, clone 4H2B10B2 Certificates of Analysis

TitleLot Number
Anti-FGFR4, clone 4H2B10B2 VP1407150
Anti-FGFR4, clone 4H2B10B2 - VP1907128 VP1907128
Anti-FGFR4, clone 4H2B10B2 - VP2401317 VP2401317
Anti-FGFR4, clone 4H2B10B2 -VP1608104 VP1608104
Anti-FGFR4, clone 4H2B10B2 Monoclonal Antibody VP1705254
Anti-FGFR4, clone 4H2B10B2 Monoclonal Antibody VP1806088
Anti-FGFR4, clone 4H2B10B2 Monoclonal Antibody VP1702155