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ABF32 Anti-Fibroblast-specific Protein 1 (S100A4) Antibody

This Anti-Fibroblast-specific Protein 1 (S100A4) Antibody is validated for use in WB, IC for the detection of Fibroblast-specific Protein 1 (S100A4).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research, Inflammation & Immunology Research Sub-Category: Ion & Transport Channels, Inflammation & Autoimmune Mechanisms Gene Symbol: S100A4, CAPL, MTS1 UniProt Number: P26447
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ABF32
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, R, B, Ca, EqWB, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF32
DescriptionAnti-Fibroblast-specific Protein 1 (S100A4) Antibody
Alternate Names
  • Protein S100-A4
  • Calvasculin
  • Metastasin
  • Placental calcium-binding protein
  • Protein Mts1
  • S100 calcium-binding protein A4
Background InformationS100A4, also known as Fibroblast-specific Protein 1, is a member of the Ca2+- dependent S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 is a metastasis factor that may function in motility, invasion, and tubulin polymerization. Increased expression of S100A4 has been associated with various types of cancer.
References
Product Information
FormatAffinity Purified
Control
  • HeLa cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Fibroblast-specific Protein 1 (S100A4) Antibody is validated for use in WB, IC for the detection of Fibroblast-specific Protein 1 (S100A4).
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: A 1:500 dilution from a representative lot detected S100A4 in mouse neural stem cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human S100A4.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes S100A4 at the C-terminus.
Species Reactivity
  • Human
  • Mouse
  • Rat
  • Bovine
  • Canine
  • Horse
Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat.
Predicted to react with Bovine, Canine, and Equine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
Gene Symbol
  • S100A4
  • CAPL
  • MTS1
Purification MethodAffinity Purfied
UniProt Number
UniProt SummarySUBUNIT STRUCTURE: Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode.

TISSUE SPECIFICITY: Ubiquitously expressed.

SEQUENCE SIMILARITIES: Belongs to the S-100 family.

Contains 2 EF-hand domains.
Molecular Weight~12 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected S100A4 in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABF32 04053252757679

Documentation

Anti-Fibroblast-specific Protein 1 (S100A4) Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Fibroblast-specific Protein 1 (S100A4) Antibody Certificates of Analysis

TitleLot Number
Anti-Fibroblast-specific Protein 1 (S100A4) - 2147118 2147118
Anti-Fibroblast-specific Protein 1 (S100A4) - 2049261 2049261
Anti-Fibroblast-specific Protein 1 (S100A4) - 2246830 2246830
Anti-Fibroblast-specific Protein 1 (S100A4) - 2297275 2297275
Anti-Fibroblast-specific Protein 1 (S100A4) - 2327497 2327497
Anti-Fibroblast-specific Protein 1 (S100A4) - 2363615 2363615
Anti-Fibroblast-specific Protein 1 (S100A4) - 2490720 2490720
Anti-Fibroblast-specific Protein 1 (S100A4) - 3231929 3231929
Anti-Fibroblast-specific Protein 1 (S100A4) - 3270768 3270768
Anti-Fibroblast-specific Protein 1 (S100A4) - 3499846 3499846
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Categories

Life Science Research > Antibodies and Assays > Primary Antibodies