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07-1401-AF488 Anti-GLUT-1 Antibody, CT, Alexa Fluor® 488 Conjugate

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07-1401-AF488
100 µL  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RICCRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue Number07-1401-AF488
DescriptionAnti-GLUT-1 Antibody, CT, Alexa Fluor® 488 Conjugate
Alternate Names
  • Solute carrier family 2, facilitated glucose transporter member 1
  • Glucose transporter type 1, erythrocyte/brain
  • GLUT-1
  • HepG2 glucose transporter
  • GLUT-1, CT, Alexa Fluor® 488 Conjugate
Background InformationSolute carrier family 2, facilitated glucose transporter member 1 (UniProt P11166; also known as Glucose transporter type 1 erythrocyte/brain, GLUT-1, HepG2 glucose transporter, Human T-cell leukemia virus I and II receptor, Receptor for HTLV-1 and HTLV-2) is encoded by the SLC2A1 (also known as DYT9, DYT17, DYT18, EIG12, GLUT, GLUT1, HTLVR, GLUT1DS, PED) gene (Gene ID 6513) in human. Glucose transporters (GLUT-1 to GLUT-7) constitute a family of integral membrane glycoproteins that facilitate cellular glucose uptake. In addition to mediateing glucose uptake in adult tissues, GLUT-1 is the predominant glucose transporter in embryonic and fetal tissues. Two forms of GLUT-1 are found in human frontal cortex, the 55 kDa form of GLUT1 regulates import of glucose from blood to brain across the endothelial cells of the blood-brain barrier (BBB), whereas the 45 kDa form of GLUT1 predominantly regulates nonvascular glial glucose uptake.
References
Product Information
FormatAlexaFluor®488
PresentationPurified rabbit conjugate antibody in PBS with 15 mg/ml BSA and 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-GLUT-1 Antibody, CT, Alexa Fluor® 488 Conjugate is validated for use in Immunocytochemistry for the detection of GLUT-1.
Key Applications
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: A 1:100 dilution from a representative lot detected GLUT-1 in HeLa and NIH/3T3 cells.
The unconjugated antibody (Cat. No. 07-1401) is shown to be suitable also for ELISA, Western blotting, immunocytochemistry, and immunohistochemistry applications.
Biological Information
ImmunogenSynthetic peptide corresponding amino acids with the C-terminus of human GLUT-1 coupled to KLH (C-ELFHPLGADSQV).
EpitopeC-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityThis antibody recognizes GLUT-1.
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Feline, Bovine, Porcine, Equine, Monkey based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • SLC2A1
  • GLUT1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~54 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in A431 cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected GLUT-1 in A431 cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
07-1401-AF488 04055977296501

Documentation

Anti-GLUT-1 Antibody, CT, Alexa Fluor® 488 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-GLUT-1 Antibody, CT, Alexa Fluor® 488 Conjugate Certificates of Analysis

TitleLot Number
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate 2966304
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate 2842869
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 3174745 3174745
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 3378584 3378584
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 3444352 3444352
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 3749941 3749941
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 3917393 3917393
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 4055469 4055469
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 4088379 4088379
Anti-GLUT-1, CT, Alexa Fluor® 488 Conjugate - 4123360 4123360

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