Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

ABN999 Anti-Gustducin alpha-3 chain

Anti-Gustducin alpha-3 chain Antibody is an antibody against Gustducin alpha-3 chain for use in Immunohistochemistry and Immunocytochemistry.

Anti-Gustducin alpha-3 chain MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Gene Symbol: GNAT3 UniProt Number: A8MTJ3
ABN999
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN999
DescriptionAnti-Gustducin alpha-3 chain
Alternate Names
  • Gustducin alpha-3 chain
  • Guanine nucleotide-binding protein G(t) subunit alpha-3
Background InformationGustducin alpha-3 chain is a G protein alpha subunit of the taste receptors and it plays a critical role in bitter, sweet and umami (MSG) taste transduction. Gustducin alpha-3 chain operates via the cGMP-phosphodiesterase signaling pathway and is mediated with calcium. Gustducin alpha-3 chain also functions in lumenal sugar sensors in the gut and may modulate the gut capacity to absorb sugars and thus play roles in malabsorption syndromes and diet related disorders including diabetes type II and obesity. Gustducin alpha-3 chain is localized to the cytoplasm and plasmalemmal being a G protein subunit. Gustducin alpha-3 chain is expressed in tastebuds and in the gut in enteroendocrine L cells, and surprisingly in spermatozoa.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Gustducin alpha-3 chain Antibody is an antibody against Gustducin alpha-3 chain for use in Immunohistochemistry and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected Gustducin alpha-3 chain in human ileum and rat testis tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Gustducin alpha-3 chain near the C-terminal.
EpitopeNear C-terminal
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Rat
Species Reactivity NoteHuman, Rat. Predicted to react with Bovine, Mouse, Hamster, Chimpanzee based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • GNAT3
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~50 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human tongue tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Gustducin alpha-3 chain in 10 µg of human tongue tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABN999 04055977135275