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ABS433 Anti-IL-32 Antibody

Anti-IL-32 Antibody is a highly specific rabbit polyclonal antibody, that targets IL-32 & has been tested in western blotting, IHC & Immunofluorescence.

Anti-IL-32 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: IL32 UniProt Number: P24001
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ABS433
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS433
DescriptionAnti-IL-32 Antibody
Alternate Names
  • Interleukin-32
  • IL-32
  • Natural killer cells protein 4
  • Tumor necrosis factor alpha-inducing factor
  • NK4
  • TAIF
Background InformationInterleukin-32 (IL-32), also known as Natural killer cells protein 4 (NK4) and Tumor necrosis factor alpha-inducing factor (TAIF), may play a role in innate and adaptive immune responses. IL-32 induces various cytokines such as TNFA/TNF-alpha, MIP-2 and IL-8, and activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. IL-32 has been shown to be induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN gamma, and it has been suggested to play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis. IL-32 is different from other known cytokine families because it does not share sequence homology with them and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. IL-32 is selectively expressed in lymphocytes and expression is more prominent in immune cells than in non-immune cells. The expression of IL-32 increased after activation of T-cells by mitogens and after activation of NK cells by IL2/interleukin-2.
References
Product Information
FormatAffinity Purified
Control
  • Human spleen tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-IL-32 Antibody is a highly specific rabbit polyclonal antibody, that targets IL-32 & has been tested in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 10 µg/mL from a representative lot detected IL-32 in human spleen tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected IL-32 in human spleen cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human IL-32.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes two isoforms at ~14 kDa and ~22 kDa at the C-terminus of IL-32.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • IL32
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~14 kDa and ~22 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 5 isoforms between ~15 kDa and ~27 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in human spleen tissue lysate.

Western Blot Analysis: 5 µg/mL of this antibody detected IL-32 in 15 µg of human spleen tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABS433 04053252910166