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MAB1155 Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2

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MAB1155
50 µg  
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Overview

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFC, IP, IHC, FUNCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB1155
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2
Alternate Names
  • Inteferon alpha/beta receptor 2
  • IFN-R-2
  • IFN-alpha binding protein
  • IFN-alpha/beta receptor 2
  • Interferon alpha binding protein
  • Type I Interferon receptor 2
Product Information
FormatPurified
PresentationPurified immunoglobulin. Liquid in PBS containing 0.1% bovine serum albumin (BSA).
Quality LevelMQ100
Applications
ApplicationAnti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2 is an antibody against Interferon-α/β Receptor Chain 2 for use in FC, IP, IH.
Key Applications
  • Flow Cytometry
  • Immunoprecipitation
  • Immunohistochemistry
  • Affects Function
Application NotesBiological Studies

Immunoprecipitation: (1-5 μg/mL)

Immunohistochemistry: (1μg/mL)

Flow cytometry: (1 μg/10 mL - block cells with 50% human AB serum)

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenHuman Interferon alpha/beta Receptor Chain 2
CloneMMHAR-2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityReacts with Human Interferon alpha/beta Receptor Chain 2 (CD118). Antibody neutralizes human interferon alpha receptor, interacts with extracellular domain, binds to human interferon alpha receptor with high affinity, and blocks biological action of Type I interferons.
IsotypeIgG2a
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • IFNAR2
  • IFNABR
  • IFNARB
UniProt Number
UniProt SummaryFUNCTION: Associates with IFNAR1 to form the tyoe I interferon receptor. Receptor for interferons aplha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation.
SIZE: 515 amino acids; 57,759 Da
SUBCELLULAR LOCATION: Single-pass type I membrane protein.
SIMILARITY: Belongs to the type II cytokine receptor family.
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain frozen at -20°C or below for retention of full activity, for up to 12 months. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum.
Packaging Information
Material Size50 µg
Global Trade Item Number
Catalog Number GTIN
MAB1155 04053252663758