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MABN371 Anti-KChIP2 potassium channel subunit Antibody, clone 60/73

This Anti-KChIP2 potassium channel subunit Antibody, clone 60/73 is validated for use in western blotting & IHC for the detection of KChIP2 potassium channel subunit.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Kcnip2, Kchip2 UniProt Number: Q9JM59
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MABN371
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, R, HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN371
DescriptionAnti-KChIP2 potassium channel subunit Antibody, clone 60/73
Alternate Names
  • Kv channel-interacting protein 2
  • KChIP2
  • A-type potassium channel modulatory protein 2
  • Potassium channel-interacting protein 2
Background InformationKCHIP2, also known as Kv channel-interacting protein 2 (KChIP2), or A-type potassium channel modulatory protein 2, or Potassium channel-interacting protein 2, and encoded by the gene Kcnip2/Kchip2, is the regulatory subunit of the Kv4/D Shal-type voltage gated inactivating potassium channel. KCHIP2 modulates the activities of Kv4.2 and Kv4.3 potassium channels. KCHIP2 is localized to the cell membrane but is a peripheral membrane protein. KCHIP2 is expressed in heart, brain and lung. In brain, KCHIP2 is abundantly expressed in striatum, hippocampus, and olfactory bulb, but moderate to low expression is seen in cerebral cortex thalamus and hypothalamus. KCHIP2 has multiple isoforms in the different tissues. Isoform 1 is predominant in cerebral cortex, striatum and hippocampus, and all three isoforms are equally expressed in olfactory bulb, but in heart only isoform 3 predominates.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-KChIP2 potassium channel subunit Antibody, clone 60/73 is validated for use in western blotting & IHC for the detection of KChIP2 potassium channel subunit.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected KChIP2 potassium channel subunit in human cerebral cortex tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to rat KChIP2 potassium channel subunit.
Clone60/73
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody does not cross react with rat KChIP1 and KChIP3 (Prof. J. Trimmer, University of California, Davis).
IsotypeIgG1κ
Species Reactivity
  • Mouse
  • Rat
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Kcnip2
  • Kchip2
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 35 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected KChIP2 potassium channel subunit in 10 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABN371 04053252943263

Documentation

Anti-KChIP2 potassium channel subunit Antibody, clone 60/73 Certificates of Analysis

TitleLot Number
Anti-KChIP2 potassium channel -2695329 2695329
Anti-KChIP2 potassium channel subunit, clone 60/73 - Q2355211 Q2355211
Anti-KChIP2 potassium channel subunit, clone 60/73 - 3277104 3277104
Anti-KChIP2 potassium channel subunit, clone 60/73 - 3670715 3670715
Anti-KChIP2 potassium channel subunit, clone 60/73 -2653163 2653163
Anti-KChIP2 potassium channel subunit, clone 60/73 Monoclonal Antibody 2970637