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MABC155 Anti-KIF3A Antibody, clone 4F9.1

This Anti-KIF3A Antibody, clone 4F9.1 is validated for use in Western Blotting and Immunohistochemistry for the detection of KIF3A.

Anti-KIF3A Antibody, clone 4F9.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: KIF3, KIF3A UniProt Number: Q9Y496
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MABC155
100 μg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC155
DescriptionAnti-KIF3A Antibody, clone 4F9.1
Alternate Names
  • Microtubule plus end-directed kinesin motor 3A
  • KIF3A
  • Kinesin-like protein KIF3A
Background InformationKinesin-like protein KIF3A (UniProt Q9Y496; also known as Kinesin family protein 3A, Microtubule plus end-directed kinesin motor 3A) is encoded by the KIF3A (also known as FLA10, KIF3, KLP-20) gene (Gene ID 11127) in human. Kinesin-2 is a heterotrimeric motor protein composed of two kinesin-related subunits, KIF3A and KIF3B, and an associated protein KAP3. The kinesin-2 motor KIF3A/B drives intraflagellar transport (IFT) of tubulins and other axonemal building blocks in cilia and flagella, pigment granules in melanosomes, and vesicles in neurons. Defects in these transport processes are linked to polycystic kidney disease and neurodegenerative diseases.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-KIF3A Antibody, clone 4F9.1 is validated for use in Western Blotting and Immunohistochemistry for the detection of KIF3A.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected KIF3A in 10 µg of rat hippocampus tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected KIF3A in human cerebellum and human cerebral cortex tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminal of human KIF3A.
Epitope C-terminal
Clone4F9.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • KIF3
  • KIF3A
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~75 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse cerebellum tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected KIF3A in 10 µg of mouse cerebellum tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABC155 04055977181593