Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

ABN337 Anti-LRFN4 Antibody

Detect the LRFN4 protein using this Anti-LRFN4 validated for use in WB & IHC.

Anti-LRFN4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: LRFN4 UniProt Number: Q6PJG9
View Products on Sigmaaldrich.com
ABN337
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN337
DescriptionAnti-LRFN4 Antibody
Alternate Names
  • Leucine-rich repeat and fibronectin typeIII domain-containing protein 4
  • synaptic adhesion-like molecule 3
  • SALM3
  • FIGLER6
Background InformationLRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the LRFN proteins play a role in the developing and/or mature vertebrate nervous system.
References
Product Information
FormatAffinity Purified
Control
  • Mouse brain tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Quality LevelMQ300
Applications
ApplicationDetect the LRFN4 protein using this Anti-LRFN4 validated for use in WB & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected LRFN4 in mouse brain tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human LRFN4.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody is predicted to not cross-react with other members of the LRFN family.
Species Reactivity
  • Mouse
  • Human
Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody TypePolyclonal Antibody
Gene Symbol
  • LRFN4
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~80 kDa observed. Uncharacterized bands may appear between ~40 and ~160 kDa in some lysates. The calculated molecular weight of this protein is 66 kDa, but can be observed at ~80 kDa due to high glycosylation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected LRFN4 in 10 µg/mL of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABN337 04053252831164