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AB3521 Anti-Leptin Antibody

Detect Leptin using this Anti-Leptin Antibody validated for use in ELISA & WB.

Anti-Leptin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Lipid Metabolism & Weight Regulation Gene Symbol: LEP, leptin, OB, obesity, OBS UniProt Number: P41159
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AB3521
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RELISA, WBChAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3521
ReplacesMAB3870
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Leptin Antibody
References
Product Information
FormatAffinity Purified
HS Code3002 15 90
PresentationAffinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Leptin using this Anti-Leptin Antibody validated for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Application NotesImmunoblotting: 1:1,000-1:5,000

ELISA: 1:1,000-1:5,000

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenRecombinant rat leptin.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostChicken
SpecificityLeptin, rat and mouse.
Species Reactivity
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Gene Symbol
  • LEP
  • leptin
  • OB
  • obesity
  • OBS
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
SIZE: 167 amino acids; 18641 Da
SUBUNIT: Interacts with SIGLEC6.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
AB3521 04053252370854

Documentation

Anti-Leptin Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Leptin Antibody Certificates of Analysis

TitleLot Number
CHICKEN ANTI-LEPTIN, RAT/MOUSE - 3384860 3384860
CHICKEN ANTI-LEPTIN, RAT/MOUSE -2703729 2703729
CHICKEN ANTI-LEPTIN, RAT/MOUSE AFFINITY PURIFIED POLYCLONAL ANTIBODY 2967777
CHICKEN ANTI-LEPTIN, RAT/MOUSE AFFINITY PURIFIED POLYCLONAL ANTIBODY 3053456
CHICKEN ANTI-LEPTIN, RAT/MOUSE AFFINITY PURIFIED POLYCLONAL ANTIBODY - 3928785 3928785
CHICKEN ANTI-LEPTIN, RAT/MOUSE AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2231585 2231585
CHICKEN ANTI-LEPTIN, RAT/MOUSE AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2376662 2376662