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MAB1281C3 Anti-Nuclei Antibody, clone 235-1, Cy3 conjugate

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MAB1281C3
100 µL  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCMCy3Monoclonal Antibody
Description
Catalogue NumberMAB1281C3
DescriptionAnti-Nuclei Antibody, clone 235-1, Cy3 conjugate
Alternate Names
  • HuNu
Background InformationCell replacement techniques such as stem-cell or fetal-cell therapies show great promise for many diseases. Cross-species grafting between human and animal cells or tissues requires the identification and localization of the donor material in the host environment. Antibodies to human-specific nuclei are useful cytological and histological markers for identifying human cells in xenograft models. MAB1281 stains nuclei of all human and primate cell types giving a diffuse nuclear staining pattern. Chromosomes are negatively stained in metaphase cells. The antibody does not react with nuclei from mouse or rat.
References
Product Information
FormatCy3
Control
  • Human foreskin fibroblasts (SCC058)
PresentationPurified mouse monoclonal IgG1 conjugated to Cy3 in PBS with 0.1% sodium azide and 15mg/ml BSA.
Quality LevelMQ100
Applications
ApplicationThe anti-Nuclei, clone 235-1, Cy3 conjugate will recognize human cell nuclei only & is usefull in xenograph transplantation studies to study stem cell migration.
Key Applications
  • Immunocytochemistry
Application NotesEvaluated by Immunocytochemistry in human bone marrow mesenchymal stem cells (SCR108). Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected nuclei in human bone marrow mesenchymal stem cells (SCR108). Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected nuclei in H9 human embryonic stem cells. Evaluated by Immunocytochemistry in mouse embryonic fibroblasts. Immunocytochemistry Analysis: A 1:50 dilution of this antibody did not detect nuclei in mouse embryonic fibroblasts.
Biological Information
ImmunogenHuman nuclei
CloneClone 235-1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Purification MethodProtein G Purified
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in human foreskin fibroblasts (SCC058). Immunocytochemistry Analysis: A 1:50 dilution of this antibody detected nuclei in human foreskin fibroblasts (SCC058).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MAB1281C3 04053252819551

Documentation

Anti-Nuclei Antibody, clone 235-1, Cy3 conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-Nuclei Antibody, clone 235-1, Cy3 conjugate Certificates of Analysis

TitleLot Number
Anti-Nuclei, clone 235-1, Cy3 -2631158 2631158
Anti-Nuclei, clone 235-1, Cy3 Conjugate 2942517
Anti-Nuclei, clone 235-1, Cy3 Conjugate 2965140
Anti-Nuclei, clone 235-1, Cy3 Conjugate 2999798
Anti-Nuclei, clone 235-1, Cy3 conjugate 3157522
Anti-Nuclei, clone 235-1, Cy3 conjugate 2468182
Anti-Nuclei, clone 235-1, Cy3 conjugate 2905395
Anti-Nuclei, clone 235-1, Cy3 conjugate 3062287
Anti-Nuclei, clone 235-1, Cy3 conjugate 2745942
Anti-Nuclei, clone 235-1, Cy3 conjugate - 2420537 2420537