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AB9822-200UL Anti-P2Y13 Receptor Antibody

Detect P2Y13 Receptor using this Anti-P2Y13 Receptor Antibody validated for use in IH & WB.

Anti-P2Y13 Receptor Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurotransmitters & Receptors Gene Symbol: P2RY13, P2Y13, FKSG77, SP174, GPR94, GPCR1, GPR86 UniProt Number: Q9BPV8
AB9822-200UL
200 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RIHC, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9822-200UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-P2Y13 Receptor Antibody
References
Product Information
FormatAffinity Purified
Control
  • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
PresentationLyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Quality LevelMQ100
Applications
ApplicationDetect P2Y13 Receptor using this Anti-P2Y13 Receptor Antibody validated for use in IH & WB.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application NotesWestern blot: 1:200 using ECL on rat brain membranes.

Immunohistochemistry on rat testis, paraffin embedded tissue.

Dilutions should be made using a carrier protein such as BSA (1-3%).

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenPurified peptide from amino acids 119-134 of human P2Y13
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Rat
Species Reactivity NoteThe immunogen sequence is 11 of 16 amino acids identical in mouse.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. Two transcript variants encoding the same protein have been identified for this gene.
Gene Symbol
  • P2RY13
  • P2Y13
  • FKSG77
  • SP174
  • GPR94
  • GPCR1
  • GPR86
Purification MethodImmunoAffinity Purified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9BPV8 # Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.
SIZE: 333 amino acids; 38440 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined.
SIMILARITY: SwissProt: Q9BPV8 ## Belongs to the G-protein coupled receptor 1 family.
MISCELLANEOUS: Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
AB9822-200UL 04053252507250