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ABC327 Anti-PD-L2 Antibody

Anti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.

Anti-PD-L2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2 UniProt Number: Q9BQ51
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ABC327
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IH(P), IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC327
DescriptionAnti-PD-L2 Antibody
Alternate Names
  • Programmed cell death 1 ligand 2
  • PD-1 ligand 2
  • PD-L2
  • PDCD1 ligand 2
  • Programmed death ligand 2
  • Butyrophilin B7-DC
  • B7-DC
  • CD273
Background InformationProgrammed cell death ligand 2 (PD-L2, PD-1 ligand 2, PDCD1 ligand 2), also known as Butyrophilin B7-DC (B7-DC), is a member of the BTN/MOG family and immunoglobulin superfamily which is thought to act as a negative regulator of T cell activation. PD-L2 may play a role in stimulating an immunogenic response through an alternative receptor from PD-1. PD-L2 is highly expressed in heart, placenta, pancreas, lung, and liver and weakly expressed in spleen, lymph nodes, and thymus.
References
Product Information
FormatAffinity Purified
Control
  • Raji cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PD-L2 in mouse brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PD-L2 in mouse brain cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human PD-L2.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody only recognizes the largest isoform at ~31 kDa.
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • PDCD1LG2
  • B7DC
  • CD273
  • PDCD1L2
  • PDL2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~31 kDa observed. Uniprot describes 2 isoforms at ~21 kDa and one isoform at ~31 kDa. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Raji cell lysate

Western Blotting Analysis: 2 µg/mL of this antibody detected PD-L2 in 15 µg of Raji cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABC327 04053252901331