Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

ABT253 Anti-Periostin Antibody (C-term)

Anti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting.

Anti-Periostin Antibody (C-term) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: Postn, OSF-2 UniProt Number: Q62009
View Products on Sigmaaldrich.com
ABT253
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT253
DescriptionAnti-Periostin Antibody (C-term)
Alternate Names
  • Periostin
  • PN
  • Osteoblast-specific factor 2
  • OSF-2
Background InformationPeriostin, also known as PN, or Osteoblast-specific factor 2 (OSF-2), and encoded by the gene POSTN/OSF2, is a secreted extracellular matrix protein that appears to be involved in inducing cell attachment and spreading as well as cell adhesion. In bone, Periostin enhances mineralization and assists in the incorporation of BMP1 protein into the fibronectin extracellular matrix of connective tissues. Periostin is preferentially expressed in periosteum and periodontal ligaments but can also be found expressed in developing heart and other tissues. Periostin is also over expressed in many cancers where is contributes to a growth-supportive role for such cancers and also aids in chemoresistance for cancers cells through the activation of the PI3K/Akt/surviving pathway.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
Immunogen A 188-amino acid bacterial fusion protein from the C-terminal region of mouse periostin.
EpitopeC-terminus
Concentration1 mg/mL
HostRabbit
SpecificityThis antibody detects a subset of splice variants of Periostin.
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Postn
  • OSF-2
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~80-85 kDa observed. Multiple splice variants detected.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse lung tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Periostin in 10 µg of mouse lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABT253 04053252976865