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ABT275 Anti-Pro-Decorin Antibody

Anti-Pro-Decorin Antibody is an antibody against Pro-Decorin for use in Immunohistochemistry.

Anti-Pro-Decorin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: DCN, SLRR1B UniProt Number: P07585
ABT275
100 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MIHCRbSerumPolyclonal Antibody
Description
Catalogue NumberABT275
DescriptionAnti-Pro-Decorin Antibody
Alternate Names
  • Decorin
  • Pro-Decorin
  • Bone proteoglycan II
  • PG-S2
  • PG40
Background InformationDecorin (UniProt P07585; also known as Bone proteoglycan II, PG40, PG-S2) is encoded by the DCN (also known as DSCD, DSPG2, PGII, PGS2, SLRR1B) gene (Entrez Gene ID 1634) in human. Decorin is a pericellular matrix proteoglycan structurally related to two other small proteoglycans, biglycan and fibromodulin. Decorin and biglycan are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while biglycan contains two chains. Decorin modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-beta (TGFbeta) superfamily. Decorin is initially translated as a preproprotein with an N-terminal signal peptide (aa1-16) and propeptide (aa17-30) sequence. Sequential removal of the signal peptide and the propeptide sequence produces pro- and mature decorin, respectively. (PMID 20026052).
References
Product Information
FormatSerum
PresentationRabbit polyclonal antibody serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Pro-Decorin Antibody is an antibody against Pro-Decorin for use in Immunohistochemistry.
Key Applications
  • Immunohistochemistry
Biological Information
ImmunogenLPH-conjugated linear peptide corresponding to the signal and propeptide of human Pro-Decorin.
EpitopeSignal and propeptide
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityReacts with decorin preproprotein (359aa) and prodecorin (347aa), but not any of the mature decorin isoforms lacking the N-terminal signal and propeptide sequence. This polyclonal antiserum is also known by LF-110.
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteHuman, Mouse. Predicted to react with Monkey, Rat, Dog, Cat, Horse, and Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • DCN
  • SLRR1B
Purification MethodUnpurified
UniProt Number
Molecular Weight39.7 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in human and mouse skin tissue.

Immunohistochemistry Analysis: A 1:200 dilution of this antibody detected Pro-Decorin in human and mouse skin tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABT275 04055977169249