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AB3258 Anti-Puromycin Sensitive Aminopeptidase Antibody

This Anti-Puromycin Sensitive Aminopeptidase Antibody is validated for use in WB, IC for the detection of Puromycin Sensitive Aminopeptidase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Enzymes & Biochemistry Gene Symbol: NPEPPS, MP100, PSA, EC 3.4.11.- UniProt Number: P55786
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AB3258
50 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWB, ICCGtPurifiedPolyclonal Antibody
Description
Catalogue NumberAB3258
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Puromycin Sensitive Aminopeptidase Antibody
References
Product Information
FormatPurified
PresentationPurified immunoglobulin. Liquid in phosphate buffered saline.
Quality LevelMQ100
Applications
ApplicationThis Anti-Puromycin Sensitive Aminopeptidase Antibody is validated for use in WB, IC for the detection of Puromycin Sensitive Aminopeptidase.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesWestern blot: 1:1,000

Immunocytochemistry: 1:1,000

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenRat puromycin sensitive aminopeptidase.
HostGoat
SpecificityRecognizes puromycin sensitive aminopeptidase.

SPECIES REACTIVITIES: It is expected that the antibody may react with other species. Reactivity with other species has not been confirmed.
Species Reactivity
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.
Gene Symbol
  • NPEPPS
  • MP100
  • PSA
  • EC 3.4.11.-
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P55786 # Aminopeptidase with broad substrate specificity to several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity (By similarity).
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
SIZE: 919 amino acids; 103276 Da
SUBCELLULAR LOCATION: Cytoplasm (Potential). Nucleus (Potential).
SIMILARITY: SwissProt: P55786 ## Belongs to the peptidase M1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
AB3258 04053252282928

Documentation

Anti-Puromycin Sensitive Aminopeptidase Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Puromycin Sensitive Aminopeptidase Antibody Certificates of Analysis

TitleLot Number
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE 3073338
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE POLYCLONAL ANTIBODY - 2383057 2383057
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE POLYCLONAL ANTIBODY - 2446734 2446734
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3266811 3266811
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3547785 3547785
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3795238 3795238
GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3939230 3939230

References

Reference overviewPub Med ID
Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro
Sengupta, Soma, et al.
Biochemistry, 45:15111-15119 (2006)  2006

17154549 17154549
Studies on the tissue distribution of the puromycin-sensitive enkephalin-degrading aminopeptidases
McLellan, S, et al.
J. Neurochem., 51:1552-1559 (1988)  1988

3171591 3171591