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MABC82 Anti-RIP1/RIPK1 Antibody, clone 3C6.1

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MABC82
100 µg  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC82
ReplacesMABC688
DescriptionAnti-RIP1/RIPK1 Antibody, clone 3C6.1
Alternate Names
  • Receptor-interacting serine/threonine-protein kinase 1
  • Cell death protein RIP
  • Receptor-interacting protein 1
  • RIP-1
  • Serine/threonine-protein kinase RIP
Background InformationReceptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect RIP1/RIPK1 using this Anti-RIP1/RIPK1 Antibody, clone 3C6.1 validated for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human RIP1/RIPK1.
Clone3C6.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • RIPK1
  • RIP
  • RIP1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 76 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected RIP1/RIPK1 in 200 µg of Jurkat cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABC82 04053252946011