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ABE1313 Anti-SMARCD3 Antibody

ABE1313
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE1313
DescriptionAnti-SMARCD3 Antibody
Alternate Names
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
  • SMARCD3
  • 60 kDa BRG-1/Brm-associated factor subunit C
  • BRG1-associated factor 60C
  • BAF60C
Background InformationSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (UniProt Q6STE5; also known as 60 kDa BRG-1/Brm-associated factor subunit C, BAF60C, BRG1-associated factor 60C, Chromatin remodeling complex BAF60C subunit, Mammalian chromatin remodeling complex BRG1-associated factor 60C, SWI/SNF complex 60 kDa subunit C, Swp73-like protein) is a nucleus protein encoded by the SMARCD3 or BAF60C gene (Entrez Gene ID 6604) in human. SMACD3/BAF60C protein belongs to the SWI/SNF family of helicases and ATPases that regulate transcriptions by modifying the chromatin structure around the target genes. Cat. No. ABE1313, Anti-SMARCD3 is an immunogen affinity purified rabbit polyclonal antibody with confirmed reactivity toward human and murine species. The immunogen peptide sequence is present in the C-terminal half of both isoform 1 (BAF60C2) and isoform 2 (BAF60C1), and is 100% conserved among human, murine, rat, feline, equine, and bovine species.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-SMARCD3 Antibody is an antibody against SMARCD3 for use in Western Blotting, Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: 2.0 µg/mL from a representative lot detected SMARCD3 in HeLa, A431, and NIH/3T3 cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the SWIB domain of human SMARCD3.
EpitopeSWIB domain
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityPredicted to cross react to both isoforms of SMARCD3.
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteHuman, Mouse. Predicted to react with Rat, Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • SMARCD3
  • BAF60C
Purification MethodAffinity
UniProt Number
Molecular Weight~58 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 5.0 µg/mL of this antibody detected SMARCD3 in 10 µg of human kidney tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABE1313 04055977169157