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MAB11041 Anti-Serotonin receptor 1A Antibody, clone 19A9.2

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Signaling Neuroscience Gene Symbol: HTR1A, 5-HT1A, 5HT1a, ADRB2RL, 5-HT-1A, ADRBRL, G-21 UniProt Number: P19327
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MAB11041
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB11041
DescriptionAnti-Serotonin receptor 1A Antibody, clone 19A9.2
Alternate Names
  • 5-hydroxytryptamine (serotonin) receptor 1A
  • 5-hydroxytryptamine receptor 1A
  • guanine nucleotide-binding regulatory protein-coupled receptor
  • Serotonin receptor 1A
  • G protein coupled receptor
  • 5-HT1a receptor
Background InformationSerotonin receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.
References
Product Information
FormatPurified
HS Code3002 15 90
Control
  • Rat brain tissue lysate
PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: 1:400 dilution from a previous lot detected Serotonin receptor 1A in normal human brain tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to rat Serotonin receptor 1A.
Clone19A9.2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgMκ
Species Reactivity
  • Rat
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryRegulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD].
Gene Symbol
  • HTR1A
  • 5-HT1A
  • 5HT1a
  • ADRB2RL
  • 5-HT-1A
  • ADRBRL
  • G-21
UniProt Number
UniProt SummaryFUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
Molecular Weight ~40 kDa observed. The calculated molecular weight is 46 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Serotonin receptor 1A on 10 µg of rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MAB11041 04053252645259

Documentation

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 SDS

Title

Safety Data Sheet (SDS) 

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 Certificates of Analysis

TitleLot Number
Anti-Serotonin receptor 1A, clone 19A9.2 - 2424802 2424802
Anti-Serotonin receptor 1A, clone 19A9.2 - 2446955 2446955
Anti-Serotonin receptor 1A, -2638890 2638890
Anti-Serotonin receptor 1A, -2776282 2776282
Anti-Serotonin receptor 1A, -2825963 2825963
Anti-Serotonin receptor 1A, clone 19A9.2 - 1951090 1951090
Anti-Serotonin receptor 1A, clone 19A9.2 - 2053404 2053404
Anti-Serotonin receptor 1A, clone 19A9.2 - 2194085 2194085
Anti-Serotonin receptor 1A, clone 19A9.2 - 2299593 2299593
Anti-Serotonin receptor 1A, clone 19A9.2 - 3289309 3289309
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