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ABF199 Anti-TIM-1 Antibody

Anti-TIM-1 Antibody is a highly specific rabbit polyclonal antibody, that targets T-cell immunoglobulin & mucin domain-containing protein 1 & has been tested in western blotting, IHC & Immunofluorescence.

Anti-TIM-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: HAVCR1 UniProt Number: Q96D42
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ABF199
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF199
DescriptionAnti-TIM-1 Antibody
Alternate Names
  • Hepatitis A virus cellular receptor 1
  • HAVcr-1
  • Kidney injury molecule 1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIMD-1
  • T-cell membrane protein 1
  • TIM-1
  • TIM
  • KIM1
  • TIM1
  • TIMD1
Background InformationT-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1, TIM-1, TIM, TIM1, TIMD1), also known as Hepatitis A virus cellular receptor 1 (HAVcr-1) and Kidney injury molecule 1(KIM-1, KIM1), may play an important role in T-helper cell development and the regulation of asthma and allergic diseases. In the case of human hepatitis A virus (HHAV) infection, TIM-1 functions as a cell-surface receptor for the virus, through which the hepatitis A virus can gain entry into a cell. Additional evidence implies that it may play a role in kidney injury and repair. TIM-1 is widely expressed, with highest levels in kidney and testis. It is also expressed by activated CD4+ T-cells during the development of helper T-cells responses. Furthermore, TIM-1 is expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge.
References
Product Information
FormatAffinity Purified
Control
  • Human uterus tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-TIM-1 Antibody is a highly specific rabbit polyclonal antibody, that targets T-cell immunoglobulin & mucin domain-containing protein 1 & has been tested in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 10 µg/mL from a representative lot detected TIM-1 in human uterus tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected TIM-1 in human uterus tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human TIM-1.
EpitopeN-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the N-terminus of TIM-1.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • HAVCR1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~48 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human uterus tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected TIM-1 in 15 µg of human uterus tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABF199 04053252910098