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ABF318 Anti-TIRP Antibody

ABF318
100 μg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF318
DescriptionAnti-TIRP Antibody
Alternate Names
  • TIR domain-containing adapter molecule 2
  • TICAM-2
  • Putative NF-kappa-B-activating protein 502
  • TRIF-related adapter molecule
  • Toll-like receptor adaptor protein 3
  • Toll/interleukin-1 receptor domain-containing protein
  • MyD88-4
Background InformationToll/interleukin-1 receptor domain-containing protein (TIRP), also known as TIR domain-containing adapter molecule 2 (TICAM2), also known as Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule (TRAM), and Toll-like receptor adaptor protein 3 (TIRAP3), is an adaptor protein containing one TIR domain, and is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) serving as an important link between the innate and adaptive immune responses. TIRP is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Quality LevelMQ300
Applications
ApplicationThis Anti-TIRP Antibody is validated for use in Western Blotting_x000D_ and Immunocytochemistry for the detection of TIRP.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis (ICC): 10 μg/mL from a representative lot detected TIRP in Raji cells.

Biological Information
ImmunogenTIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP.
EpitopeC-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • TICAM2
  • TIRAP3
  • TIRP
  • TRAM
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~27 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in PC-3 cell lysate.

Western Blotting Analysis (WB): 1 μg/mL of this antibody detected TIRP in PC-3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABF318 04055977174663