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MABF272 Anti-TREM-1, clone 2(1a2) Antibody

This Anti-TREM-1, clone 2(1a2) Antibody is validated for use in Flow Cytometry for the detection of TREM-1.

Anti-TREM-1, clone 2(1a2) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: TREM1 UniProt Number: Q9NP99
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MABF272
100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMATT-550Monoclonal Antibody
Description
Catalogue NumberMABF272
DescriptionAnti-TREM-1, clone 2(1a2) Antibody
Alternate Names
  • Triggering receptor expressed on myeloid cells 1
  • TREM-1
  • Triggering receptor expressed on monocytes 1
  • CD354
Background InformationTriggering receptor expressed on myeloid cells 1 (TREM-1) is a membrane bound protein and secreted protein that is expressed by most cells in many tissues including liver, lung, spleen, lymph node, heart, and even spinal cord in response to bacterial and fungal infections. TREM-1 stimulates neutrophil and monocyte mediated inflammatory responses. TREM-1 also triggers pro-inflammatory chemokines and cytokines as well as increases surface expression of cell activation markers like CD11, thus TREM-1 acts as an amplifier of inflammatory responses in response to these pathogens. TREM-1 similarly is a potent LPS response factor and its expression is upregulated by LPS released by bacterial and fungal infections, and thus TREM-1 is a critical mediator of septic shock caused by such infections.
References
Product Information
FormatATT-550
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-TREM-1, clone 2(1a2) Antibody is validated for use in Flow Cytometry for the detection of TREM-1.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenRecombinant protein corresponding to human TREM-1.
Clone2(1a2)
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TREM1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight26 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Flow Cytometry in human peripheral blood mononuclear.

Flow Cytometry Analysis: 0.25 µg of this antibody detected TREM-1 in human peripheral blood mononuclear cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABF272 04053252996177