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MABN666 Anti-TRIP8b Antibody, clone N212A/34

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MABN666
100 µg  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, R, MWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN666
DescriptionAnti-TRIP8b Antibody, clone N212A/34
Alternate Names
  • PEX5-related protein
  • PEX5-like protein
  • Peroxin-5-related protein
  • TPR-containing Rab8b-interacting protein
  • Tetratricopeptide repeat-containing Rab8b-interacting protein
  • Pex5Rp
  • TRIP8b
Background InformationTetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) is also called PEX5-related protein, PEX5-like protein and Peroxin-5-related protein (Pex5Rp). TRIP8b a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel subunit that is involved in HCN cynclic nucleotide dependence and expression at the cell surface. TRIP8b is expressed specifically in the brain.
References
Product Information
FormatPurified
Control
  • Rat brain tissue lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-TRIP8b Antibody, clone N212A/34 is a highly specific mouse monoclonal antibody & that targets Tetratricopeptide repeat-containing Rab8b-interacting protein & has been tested in western blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of human brain tissue lysate.

Western Blotting Analysis: A representative lot detected TRIP8b in COS cell lysates transiently transfected with GFP tagged TRIP8b (exon1b) and not in COS cell lysates transiently transfected with TRIP8b (exon1a, 2, or 4) or with untagged Kv2.1 plasmid (Prof. J. Trimmer, University of California, Davis.).
Biological Information
ImmunogenRecombinant protein corresponding to rat TRIP8b.
CloneN212A/34
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody demonstrates specificity for TRIP8b containing exon 1b. It does not cross react with TRIP8b containing exons 1a, 2, or 4.
IsotypeIgG1κ
Species Reactivity
  • Human
  • Rat
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Pex5l
  • Pex2
  • Pex5r
  • Trip8b
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~70 kDa observed. Multiple isoforms may be observed due to alternative splicing (Lewis, A. S., et al. (2009). J Neurosci. 29(19):6250-6265.). Uncharacterized band(s) may be observed in some cell lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analyis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABN666 04053252916991