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ABT330 Anti-TSLP Antibody

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ABT330
100 µg  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IH(P), IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT330
DescriptionAnti-TSLP Antibody
Alternate Names
  • TSLP Antibody
  • Thymic stromal lymphopoietin
Background InformationThymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. TSLP is expressed in a number of tissues including heart, liver, and prostate.
References
Product Information
FormatAffinity Purified
Control
  • A20 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Thymic stromal lymphopoietin using this rabbit polyclonal antibody, Anti-TSLP Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected TSLP in human prostate cancer and heart tissues.

Immunofluorescence Analysis: A 20 μg/mL from a representative lot detected TSLP in human brain cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the intermediate domain of human TSLP.
EpitopeIntermediate domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the intermediate domain of TSLP.
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • TSLP
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~23 kDa observed. The calculated molecular weight of this protein is 18 kDa, but can be observed at ~23 kDa due to high glycosylation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in A20 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP in 15 µg of A20 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABT330 04053252912344