Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

ABT189 Anti-Tropomyosin 4 Antibody

View Products on Sigmaaldrich.com
ABT189
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT189
DescriptionAnti-Tropomyosin 4 Antibody
Alternate Names
  • Tropomyosin alpha-4 chain
  • TM30p1
  • Tropomyosin-4
Background InformationTropomyosin-4 is also called Tropomyosin alpha-4 chain and TM30p1. Tropomyosin-4 binds calcium and to actin filaments in muscle and non-muscle cells. Tropomyosin-4 associates with the troponin complex, and plays a role in the regulation of smooth and striated muscle contraction, as well as the stabilization of cytoskeleton actin filaments in non-muscle cells. Tropomyosin-4 is found in cardiac tissue and platelets.
References
Product Information
FormatAffinity Purified
Control
  • NIH/3T3 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Tropomyosin 4 Antibody is an antibody against Tropomyosin 4 for use in western blotting & IHC (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Tropomyosin 4 in human prostate cancer sections and human heart sections tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Tropomyosin 4.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of Tropomyosin 4.
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • TPM4
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~33 kDa observed. The calculated molecular weight is 29 kDa, however Tropomyosin 4 has been shown as a ~33 kDa band in western blots (Brooke, K., et al. (2006). Bone. 39:697-705).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: A 1:2,500 dilution of this antibody detected Tropomyosin 4 in 10 µg of NIH/3T3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABT189 04053252916090