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MABC536 Anti-Vasohibin-2, clone 5E3 Antibody

Anti-Vasohibin-2 antibody, clone 5E3 is an antibody against Vasohibin-2 for use in western blotting & IHC.

Anti-Vasohibin-2, clone 5E3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: VASH2, VASHL UniProt Number: Q86V25
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MABC536
100 µg  
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Overview

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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC536
DescriptionAnti-Vasohibin-2, clone 5E3 Antibody
Alternate Names
  • Vasohibin-2
  • Vasohibin-like protein
Background InformationVasohibin-2, also known as Vasohibin-like protein, and encoded by the gene VASH2/VASHL, is a developmental regulator protein of angiogenesis induced by VEGF and present in various embryonic organs at six to 12 twelve weeks of development in humans. Vasohibin-2 acts as an angiogenesis inhibitor and is thought to help regulate organ vessel formation and maturation. In cancer, Vascohibin-2 appears to act to promote angiogenesis and is expressed in many cancers. In cancer cells, there are two isoforms. VASH2 (with 355 amino acid residues) is located in the cytoplasm while VASH2 (with 311 amino acid residues) is located in the nucleus. The former was found to be a relatively low abundance protein.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing PBS without preservatives .
Quality LevelMQ100
Applications
ApplicationAnti-Vasohibin-2 antibody, clone 5E3 is an antibody against Vasohibin-2 for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Vasohibin 2 in human placenta tissue.
Immunohistochemistry Analysis: A representative lot detected Vasohibin 2 in human and mouse embryonic lung tissue (Shibuya, T., et al. (2006). American Heart Association. 26:1051-1057).
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Vasohibin 2.
Clone5E3
Concentration1 mg/mL
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • VASH2
  • VASHL
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~40 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HUVEC cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Vasohibin 2 in 10 µg of HUVEC cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABC536 04053252975752

Documentation

Anti-Vasohibin-2, clone 5E3 Antibody Certificates of Analysis

TitleLot Number
Anti-Vasohibin-2, clone 5E3 3083528
Anti-Vasohibin-2, clone 5E3 - Q2426884 Q2426884
Anti-Vasohibin-2, clone 5E3 - 3229377 3229377
Anti-Vasohibin-2, clone 5E3 - 3385863 3385863
Anti-Vasohibin-2, clone 5E3 - 3819208 3819208
Anti-Vasohibin-2, clone 5E3 - 3862697 3862697
Anti-Vasohibin-2, clone 5E3 - 4159886 4159886
Anti-Vasohibin-2, clone 5E3 -2717553 2717553
Anti-Vasohibin-2, clone 5E3 Monoclonal Antibody 2923051
Anti-Vasohibin-2, clone 5E3 Monoclonal Antibody 3559007

References

Reference overviewPub Med ID
Isolation and characterization of vasohibin-2 as a homologue of VEGF-inducible endothelium-derived angiogenesis inhibitor vasohibin.
Shibuya, Takumi, et al.
Arterioscler. Thromb. Vasc. Biol., 26: 1051-7 (2006)  2006

Show Abstract 		16528006 16528006