Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

ABE18-AF488 Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate Antibody

This Anti-acetyl Histone H3 (Lys9) is validated for use in Immunocytochemistry for the detection of acetyl Histone H3 (Lys9).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Nuclear Receptors Gene Symbol: HIST3H3, H3FT UniProt Number: Q16695
View Products on Sigmaaldrich.com
ABE18-AF488
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue NumberABE18-AF488
DescriptionAnti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate Antibody
Alternate Names
  • Histone H3.1t
  • H3/t
  • H3t
  • H3/g
  • acetyl Histone H3 (Lys9)
Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely by acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1α. The enzymes responsible for H3K9 trimethylation are SUV39H1 and SUV39H2.
References
Product Information
FormatAlexaFluor®488
PresentationPurified rabbit IgG in PBS containing 15 mg/mL BSA and 0.1% Sodium Azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-acetyl Histone H3 (Lys9) is validated for use in Immunocytochemistry for the detection of acetyl Histone H3 (Lys9).
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenLinear peptide corresponding to acetyl Histone H3 (Lys9).
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Mouse, Chicken based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HIST3H3
  • H3FT
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight17 kDa observed. Molecular weight was observed with parent ABE18.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in A431 cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected acetyl Histone H3 (Lys9) in A431 cells. ABE18-AF488 is derived from its parent antibody ABE18.
Alexa Fluor® is a registered trademark of Life Technologies®.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABE18-AF488 04053252982637

Documentation

Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate Antibody Certificates of Analysis

TitleLot Number
Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate - Q2438616 Q2438616
Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate - 3536094 3536094
Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate - 4071277 4071277
Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate_2829443 2829443

Related Products & Applications

Product Families

Conjugated Antibodies for Chromatin Analysis

EMD Millipore's Alexa Fluor® Conjugated Histone and puromycin antibodies are validated in immunocytochemistry. All EMD Millipore antibodies are based on the expertise of Upstate & Chemicon.
Learn More >>

Categories

Life Science Research > Antibodies and Assays > Primary Antibodies