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07-748-AF647 Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor® 647 Conjugate

This Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor® 647 Conjugate is validated for use in ICC for the detection of monomethyl Histone H4 (Lys20).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Histones Gene Symbol: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K,
H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 UniProt Number: Q6DRA9, P62805
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07-748-AF647
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCRbAlexaFluor®647Polyclonal Antibody
Description
Catalogue Number07-748-AF647
DescriptionAnti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor® 647 Conjugate
Alternate Names
  • Histone H4
Background InformationHistones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The histones have an amino terminal tail, a globular domain, and a carboxy-terminal tail. The four core histones, H2A, H2B, H3 and H4 assemble into the octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped in a sequence-independent manner around the octamer, forming the basic subunit of chromatin, the nucleosome. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail, H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. This product is a conjugated version of Cat. No. 07-748.
References
Product Information
FormatAlexaFluor®647
PresentationPurified rabbit conjugated antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor® 647 Conjugate is validated for use in ICC for the detection of monomethyl Histone H4 (Lys20).
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenLinear peptide corresponding to Histone H4 monomethylated at Lys20.
Concentration0.5 mg/mL
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HIST1H4A
  • H4/A
  • H4FA
  • HIST1H4B
  • H4/I
  • H4FI
  • HIST1H4C
  • H4/G
  • H4FG
  • HIST1H4D
  • H4/B
  • H4FB
  • HIST1H4E
  • H4/J
  • H4FJ
  • HIST1H4F
  • H4/C
  • H4FC
  • HIST1H4H
  • H4/H
  • H4FH
  • HIST1H4I
  • H4/M
  • H4FM
  • HIST1H4J
  • H4/E
  • H4FE
  • HIST1H4K

  • H4/D
  • H4FD
  • HIST1H4L
  • H4/K
  • H4FK
  • HIST2H4A
  • H4/N
  • H4F2
  • H4FN
  • HIST2H4
  • HIST2H4B
  • H4/O
  • H4FO
  • HIST4H4
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~10 kDa observed (Refer to Cat. No. 07-748)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H4 (Lys20) in HeLa cells.

Alexa Fluor® is a registered trademark of Life Technologies®.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
07-748-AF647 04053252971600

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Life Science Research > Antibodies and Assays > Primary Antibodies