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ABS192 Anti-phospho-SRPK2 (Ser497) Antibody

Anti-phospho-SRPK2 (Ser497) Antibody is a highly specific rabbit polyclonal antibody, that targets SRPK & has been tested in western blotting.

Anti-phospho-SRPK2 (Ser497) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: SRPK2 UniProt Number: P78362
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ABS192
200 µL  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, HtWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS192
DescriptionAnti-phospho-SRPK2 (Ser497) Antibody
Alternate Names
  • SRSF protein kinase 2
  • SFRS protein kinase 2
  • Serine/arginine-rich protein-specific kinase 2
  • SR-protein-specific kinase 2
  • SRSF protein kinase 2 N-terminal
  • SRSF protein kinase 2 C-terminal
Background InformationSRPK2 is also known as SRSF protein kinase 2, SFRS protein kinase 2, and Serine/arginine-rich protein-specific kinase 2. SRPK2 is a kinase which is involved in the phosphorylation of SR splicing factors, and the regulation of splicing. SRPK2 also promotes neuronal apoptosis, plays an essential role in splicesomal B complex formation, and mediates hepatitis B virus (HBV) replication and core protein phosphorylation. SRPK2 is highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.
References
Product Information
FormatAffinity Purified
Control
  • NIH3T3 cell lysate and Insulin treated NIH3T3 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-phospho-SRPK2 (Ser497) Antibody is a highly specific rabbit polyclonal antibody, that targets SRPK & has been tested in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the protein kinase domain of human SRPK2 (Ser497).
EpitopeProtein kinase domain
HostRabbit
SpecificityThis antibody recognizes the protein kinase domain of SRPK2 phosphorylated at Ser497.
Species Reactivity
  • Human
  • Mouse
  • Hamster
Species Reactivity NoteDemonstrated to react with Mouse, Hamster, and Human. Predicted to react with Rat and Xenopus based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • SRPK2
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~120 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing at ~77 kDa and ~79 kDa. Uniprot states 8 phosphorylation sites are known to exist.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in NIH3T3 cell lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected SRPK2 (Ser497) in 10 µg of NIH3T3 cell lysate and Insulin treated NIH3T3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABS192 04053252861499