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12-516 Axltide

Axltide MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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12-516
1 mg  
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Overview

Replacement Information
Description
Catalogue Number12-516
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAxltide
References
Product Information
PresentationLyophilized powder
Quality LevelMQ300
Applications
Key Applications
  • Kinase Assay
Biological Information
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Symbol
  • AXL
  • UFO
Protein TargetAxl
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P30530 # May function as a signal transducer between specific cell types of mesodermal origin.
SIZE: 887 amino acids; 97437 Da
SUBUNIT: Heterodimer and heterotetramer with GAS6.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
DISEASE:SwissProt: P30530 # Has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia.
SIMILARITY: SwissProt: P30530 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily. & Contains 2 fibronectin type-III domains. & Contains 2 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by for use as a substrate in protein kinase assay.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions2 years at -20°C
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
12-516 04053252508523

Documentation

Axltide SDS

Title

Safety Data Sheet (SDS) 

Axltide Certificates of Analysis

TitleLot Number
Axltide (Axl/Insulin Receptor substrate peptide) 2896061
Axltide (Axl/Insulin Receptor substrate peptide) 3041075
Axltide (Axl/Insulin Receptor substrate peptide) 3082824
Axltide (Axl/Insulin Receptor substrate peptide) - 2193174 2193174
Axltide (Axl/Insulin Receptor substrate peptide) - 2196199 2196199
Axltide (Axl/Insulin Receptor substrate peptide) - 2207274 2207274
Axltide (Axl/Insulin Receptor substrate peptide) - 2297234 2297234
Axltide - 0703054341 0703054341
Axltide - 2290365 2290365
Axltide - 24560 24560
Show more

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Categories

Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates