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GF301 BDNF Protein, Human Recombinant Animal Free

The BDNF protein is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation & survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system.

BDNF Protein, Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P23560 Entrez Gene Number: NM_001709.3, NM_170731.3, NM_170732.3, NM_170733.2, NM_170734.2, NM_170735.4
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GF301
10 µg  
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Overview

Replacement Information

Key Specifications Table

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF301
DescriptionBDNF Protein, Human Recombinant Animal Free
Alternate Names
  • Brain derived neurotrophic factor
  • Abrineurin
Background InformationBrain derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT3, and NT4/5. BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions.
References
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationThe BDNF protein is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation & survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityChicken, Frog, Mouse, Rat, Hamster, Guinea Pig, and Monkey
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
GF301 04053252691423

Documentation

BDNF Protein, Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
Recombinant Animal Free Human BDNF - 2146036 2146036
Recombinant Animal Free Human BDNF - 2383615 2383615
Recombinant Animal Free -2514254 2514254
Recombinant Animal Free -2548067 2548067
Recombinant Animal Free -2549456 2549456
Recombinant Animal Free -2585928 2585928
Recombinant Animal Free -2642212 2642212
Recombinant Animal Free -2687812 2687812
Recombinant Animal Free -2733254 2733254
Recombinant Animal Free -2748627 2748627
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