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14-675M BrSK1 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human BrSK1 amino acids 2-end, for use in Kinase Assays.

14-675M
250 µg  Also available in 10 μg size (cat#14-675) and in bulk (cat#14-675-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-675M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionBrSK1 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, human BrSK1 amino acids 2-end
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human BrSK1 amino acids 2-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Entrez Gene Number
Gene Symbol
  • BRSK1
  • SAD1
  • KIAA1811
  • FLJ43009
Protein TargetBrSK1
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q8TDC3 # Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)- induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.
COFACTOR: Magnesium.
SIZE: 794 amino acids; 86753 Da
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage.
TISSUE SPECIFICITY: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
SIMILARITY: SwissProt: Q8TDC3 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. & Contains 1 protein kinase domain. & Contains 1 UBA domain.
Molecular Weight88.4kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of CHKtide (Catalog # 12-373)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-675) and in bulk (cat#14-675-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
14-675M 04053252924934

Documentation

Related Products & Applications

Alternative Packsize

Catalog Number Description
14-675 BrSK1 Protein, active, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases