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504761 CL316243 Hydrate - CAS 138908-40-4 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate

Primary Target: →₃ adrenoceptors
504761
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
138908-40-4C₂₀H₁₈ClNNa₂O₇ • H₂O

Products

Catalog NumberPackaging Qty/Pack
5.04761.0001 Glass bottle 5 mg
Description
OverviewA very potent agonist highly selective for β3 adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of β3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
Catalogue Number504761
Brand Family Calbiochem®
SynonymsDisodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
References
ReferencesFlach, R., et al. 2013. Am. J. Pathol. 182, 886.
Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
Yoshida, T., et al. 1994. Life Sci. 54, 491.
Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.
Product Information
CAS number138908-40-4
FormLight beige powder
Hill FormulaC₂₀H₁₈ClNNa₂O₇ • H₂O
Chemical formulaC₂₀H₁₈ClNNa₂O₇ • H₂O
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target→₃ adrenoceptors
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.04761.0001 04055977244106

Documentation

References

Reference overview
Flach, R., et al. 2013. Am. J. Pathol. 182, 886.
Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
Yoshida, T., et al. 1994. Life Sci. 54, 491.
Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision31-May-2013 JSW
SynonymsDisodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
DescriptionA very potent agonist highly selective for ?3 adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of ?3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
FormLight beige powder
CAS number138908-40-4
Chemical formulaC₂₀H₁₈ClNNa₂O₇ • H₂O
Structure formulaStructure formula
Purity≥98% by HPLC
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Toxicity Standard Handling
ReferencesFlach, R., et al. 2013. Am. J. Pathol. 182, 886.
Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
Yoshida, T., et al. 1994. Life Sci. 54, 491.
Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.