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210150 Cantharidic Acid - CAS 28874-45-5 - Calbiochem

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy-endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane

Primary Target: PP2A
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210150
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
28874-45-5C₁₀H₁₄O₅

Products

Catalog NumberPackaging Qty/Pack
210150-10MG Plastic ampoule 10 mg
Description
OverviewA potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).
Catalogue Number210150
Brand Family Calbiochem®
Synonyms5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy-endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
References
ReferencesZhang, Z., et al. 1996. Biochemistry 35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.
Product Information
CAS number28874-45-5
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₀H₁₄O₅
Chemical formulaC₁₀H₁₄O₅
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPP2A
Primary Target IC<sub>50</sub>50 nM against protein phosphatase 2A
Purity>95% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
210150-10MG 04055977219142

Documentation

Cantharidic Acid - CAS 28874-45-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Cantharidic Acid - CAS 28874-45-5 - Calbiochem Certificates of Analysis

TitleLot Number
210150

References

Reference overview
Zhang, Z., et al. 1996. Biochemistry 35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.

Brochure

Title
Protein Phosphatases Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-May-2011 JSW
Synonyms5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy-endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
DescriptionInhibits protein phosphatase 2A (IC50 = 50 nM).
FormWhite solid
CAS number28874-45-5
Chemical formulaC₁₀H₁₄O₅
Structure formulaStructure formula
Purity>95% by TLC
SolubilityDMSO (25 mg/ml) or warm Ethanol (10 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesZhang, Z., et al. 1996. Biochemistry 35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.